Biomaterials Engineering
Biomaterials engineering involves the design and application of materials for in vitro assays that closely mimic the behavior of cells in living tissues.  AlphaGenix is developing biomaterials including extracellular matrix proteins in novel cell culture systems and synthetic peptide nanofibers for these purposes.  It is investigating stem cells and genetically engineered cells and their interaction with these biomaterials, which has the ability to increase the efficacy of cell therapy.

Regenerative Medicine
Regenerative medicine or cell therapy has applications for many diseases such as cardiac disease, diabetes, neurological disorders, cancer, burns, and arthritis.  AlphaGenix is investigating the use of cell therapy for the treatment of traumatic brain injury (TBI).  In a rat model of TBI, stem cell therapy after moderate TBI improves motor and cognitive function.  The placement and method of delivery are important factors in cell survival and may improve cell survival and cognitive recovery.

Biochemical Engineering of Therapeutic Proteins
The company biochemically engineers human extracellular matrix (ECM) proteins for clinical applications. These natural biomaterials play a role in treating a wide array of diseases including, but not limited to, neurological disorders and hereditary muscle diseases.  In addition, AlphaGenix's human ECM is being used as a scaffold for tissue engineering, reconstruction and repair and has shown efficacy in a xenograft tumor model in reducing tumor formation in conjunction with stem cells.